After a EDM 2.2.2 base installation on a WebSphere Application Server 9.0.5 the connection to the SOAP port was not longer possible. To solve the issue you need to follow this procedure.
You need to enable FIPS in WebSphere global security.
You need to create two custom properties in Global security:
com.ibm.jsse2.usefipsprovider = true
com.ibm.jsse2.usefipsProviderName = IBMJCEFIPS
Now restart WebSphere.